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Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19

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Science Immunology  10 Jul 2020:
Vol. 5, Issue 49, eabd1554
DOI: 10.1126/sciimmunol.abd1554

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vol. 5 no. 49

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  • Received June 4, 2020
  • Accepted July 7, 2020
  • .

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Author Information

  1. Jeong Seok Lee1,*,
  2. Seongwan Park2,*,
  3. Hye Won Jeong3,*,
  4. Jin Young Ahn4,*,
  5. Seong Jin Choi1,
  6. Hoyoung Lee1,
  7. Baekgyu Choi2,
  8. Su Kyung Nam2,
  9. Moa Sa1,5,
  10. Ji-Soo Kwon1,6,
  11. Su Jin Jeong4,
  12. Heung Kyu Lee1,5,
  13. Sung Ho Park7,
  14. Su-Hyung Park1,5,
  15. Jun Yong Choi4,,
  16. Sung-Han Kim6,,
  17. Inkyung Jung2, and
  18. Eui-Cheol Shin1,5,
  1. 1Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea.
  2. 2Department of Biological Sciences, KAIST, Daejeon 34141, Republic of Korea.
  3. 3Department of Internal Medicine, Chungbuk National University College of Medicine, Cheongju 28644, Republic of Korea.
  4. 4Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
  5. 5The Center for Epidemic Preparedness, KAIST Institute, Daejeon 34141, Republic of Korea.
  6. 6Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea.
  7. 7School of Life Sciences, Ulsan National Institute of Science & Technology (UNIST), Ulsan 44919, Republic of Korea.
  1. Corresponding author. Email: ecshin{at} (E.-C.S.); ijung{at} (I.J.); shkimmd{at} (S.-H.K.); seran{at} (J.Y.C.)
  • * These authors contributed equally to this work.


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