SARS-CoV-2 seroprevalence among parturient women in Philadelphia

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Science Immunology  29 Jul 2020:
Vol. 5, Issue 49, eabd5709
DOI: 10.1126/sciimmunol.abd5709

Monitoring SARS-CoV-2 exposure

When the SARS-CoV-2 pandemic started, stay-at-home orders led to postponement of routine medical appointments, making it difficult to perform community-level seroprevalence studies. Pregnant women, particularly those near their delivery dates, continued to have regular interactions with their medical care providers. Flannery et al. measured the exposure rate of SARS-CoV-2 in parturient women in Philadelphia who came to the hospital to deliver between 4 April and 3 June 2020. Using IgG and IgM antibody tests, they evaluated exposure of 1293 parturient women to SARS-CoV-2 and found that 6.2% of these women had evidence of exposure to the virus. They found considerable racial differences in exposure rates, with higher rates of seropositivity in Black/non-Hispanic and Hispanic/Latino women as compared with Asian and White/non-Hispanic women.

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