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Comprehensive mapping of immune perturbations associated with severe COVID-19

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Science Immunology  15 Jul 2020:
Vol. 5, Issue 49, eabd7114
DOI: 10.1126/sciimmunol.abd7114

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vol. 5 no. 49

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History: 
  • Received July 7, 2020
  • Accepted July 10, 2020
  • .

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Author Information

  1. Leticia Kuri-Cervantes1,2,*,
  2. Maria Betina Pampena1,2,*,
  3. Wenzhao Meng3,
  4. Aaron M. Rosenfeld3,
  5. Caroline A. G. Ittner4,
  6. Ariel R. Weisman4,
  7. Roseline S. Agyekum4,
  8. Divij Mathew1,5,
  9. Amy E. Baxter1,5,
  10. Laura A. Vella2,6,
  11. Oliva Kuthuru2,5,
  12. Sokratis A. Apostolidis2,5,7,
  13. Luanne Bershaw2,5,
  14. Jeanette Dougherty2,5,
  15. Allison R. Greenplate2,5,
  16. Ajinkya Pattekar2,8,
  17. Justin Kim2,5,
  18. Nicholas Han2,5,
  19. Sigrid Gouma1,2,
  20. Madison E. Weirick1,2,
  21. Claudia P. Arevalo1,2,
  22. Marcus J. Bolton1,2,
  23. Eileen C. Goodwin1,2,
  24. Elizabeth M. Anderson1,2,
  25. Scott E. Hensley1,2,
  26. Tiffanie K. Jones4,
  27. Nilam S. Mangalmurti2,4,
  28. Eline T. Luning Prak3,
  29. E. John Wherry2,5,9,,
  30. Nuala J. Meyer4, and
  31. Michael R. Betts1,2,
  1. 1Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  2. 2Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  3. 3Department of Pathology and Laboratory Medicine, Perelman School of Medicine, Philadelphia, PA 19104, USA.
  4. 4Division of Pulmonary, Allergy and Critical Care, Center for Translational Lung Biology, Lung Biology Institute, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  5. 5Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  6. 6Division of Infectious Diseases, Department of Pediatrics, Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  7. 7Division of Rheumatology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.
  8. 8Division of Gastroenterology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.
  9. 9Parker Institute for Cancer Immunotherapy at the University of Pennsylvania, Philadelphia, PA 19104, USA.
  1. Corresponding author. Email: betts{at}pennmedicine.upenn.edu (M.R.B.); nuala.meyer{at}pennmedicine.upenn.edu (N.J.M.); wherry{at}pennmedicine.upenn.edu (E.J.W.)
  • * These authors contributed equally to this work.

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