Research ArticleT CELLS

IL-21 from high-affinity CD4 T cells drives differentiation of brain-resident CD8 T cells during persistent viral infection

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Science Immunology  18 Sep 2020:
Vol. 5, Issue 51, eabb5590
DOI: 10.1126/sciimmunol.abb5590

Article Information

vol. 5 no. 51

PubMed: 
Published By: 
History: 
  • Received March 4, 2020
  • Revision received May 25, 2020
  • Accepted August 25, 2020
  • .

Author Information

  1. Heather M. Ren1,
  2. Elizabeth M. Kolawole2,
  3. Mingqiang Ren3,4,
  4. Ge Jin1,
  5. Colleen S. Netherby-Winslow1,
  6. Quinn Wade5,
  7. Shwetank1,*,
  8. Ziaur S. M. Rahman1,
  9. Brian D. Evavold2 and
  10. Aron E. Lukacher1,
  1. 1Department of Microbiology and Immunology, Penn State College of Medicine, Hershey, PA 17033, USA.
  2. 2Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City, UT 84112, USA.
  3. 3Consortium for Health and Military Performance, Department of Military & Emergency Medicine, Uniformed Services University, Bethesda, MD 20814, USA.
  4. 4Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD 20814, USA.
  5. 5Department of Neurosurgery, Penn State College of Medicine, Hershey, PA 17033, USA.
  1. Corresponding author. Email: alukacher{at}pennstatehealth.psu.edu
  • * Present address: Biocon Bristol Myers Squibb Research Centre (BBRC), Syngene Intl. Ltd., Biocon Park, Jigani Link Road, Bangalore-560100, India.

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