Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8+ T cells

See allHide authors and affiliations

Science Immunology  11 Sep 2020:
Vol. 5, Issue 51, eabb7066
DOI: 10.1126/sciimmunol.abb7066

Article Information

vol. 5 no. 51

Published By: 
  • Received March 13, 2020
  • Accepted August 20, 2020
  • .

Author Information

  1. Christian Perez-Shibayama1,
  2. Ulrika Islander2,
  3. Mechthild Lütge1,
  4. Hung-Wei Cheng1,
  5. Lucas Onder1,
  6. Sandra S. Ring1,
  7. Angelina De Martin1,
  8. Mario Novkovic1,
  9. Julia Colston3,
  10. Cristina Gil-Cruz1 and
  11. Burkhard Ludewig1,4,*
  1. 1Institute of Immunobiology, Kantonsspital St. Gallen, St. Gallen, Switzerland.
  2. 2Krefting Research Centre, Department of Internal Medicine and Clinical Nutrition, University of Gothenburg, Gothenburg, Sweden.
  3. 3Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.
  4. 4Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.
  1. *Corresponding author. Email: burkhard.ludewig{at}


Article usage

Article usage: September 2020 to September 2020

Sep 20205518462272

Stay Connected to Science Immunology