FocusDEVELOPMENTAL IMMUNOLOGY

Illuminating the core of adaptive immunity—how the regulatory genome controls Rag chromatin dynamics

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Science Immunology  04 Sep 2020:
Vol. 5, Issue 51, eabd6427
DOI: 10.1126/sciimmunol.abd6427

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Abstract

E2A specifies adaptive immunity by instructing large-scale topological changes for Rag gene super-enhancer formation (see the related Research Article by Miyazaki et al.).

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