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Research ArticleNEUROIMMUNOLOGY
Microglial autophagy–associated phagocytosis is essential for recovery from neuroinflammation
- View ORCID ProfileRasmus Berglund1,
- View ORCID ProfileAndre Ortlieb Guerreiro-Cacais1,
- Milena Z. Adzemovic1,
- Manuel Zeitelhofer2,
- View ORCID ProfileHarald Lund1,
- View ORCID ProfileEwoud Ewing1,
- Sabrina Ruhrmann1,
- Erik Nutma3,
- View ORCID ProfileRoham Parsa1,
- Melanie Thessen-Hedreul1,
- View ORCID ProfileSandra Amor3,4,
- View ORCID ProfileRobert A. Harris1,
- View ORCID ProfileTomas Olsson1,* and
- View ORCID ProfileMaja Jagodic1,*,†
- 1Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden.
- 2Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 65 Solna, Sweden.
- 3Department of Pathology, Amsterdam UMC, Location VUmc, De Boelelaan 1117, 1081 HV Amsterdam, Netherlands.
- 4Centre for Neuroscience and Trauma, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
- ↵†Corresponding author. Email: maja.jagodic{at}ki.se
↵* These authors contributed equally to this work.
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Science Immunology 16 Oct 2020:
Vol. 5, Issue 52, eabb5077
DOI: 10.1126/sciimmunol.abb5077
Vol. 5, Issue 52, eabb5077
DOI: 10.1126/sciimmunol.abb5077
Rasmus Berglund
1Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden.
Andre Ortlieb Guerreiro-Cacais
1Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden.
Milena Z. Adzemovic
1Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden.
Manuel Zeitelhofer
2Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 65 Solna, Sweden.
Harald Lund
1Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden.
Ewoud Ewing
1Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden.
Sabrina Ruhrmann
1Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden.
Erik Nutma
3Department of Pathology, Amsterdam UMC, Location VUmc, De Boelelaan 1117, 1081 HV Amsterdam, Netherlands.
Roham Parsa
1Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden.
Melanie Thessen-Hedreul
1Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden.
Sandra Amor
3Department of Pathology, Amsterdam UMC, Location VUmc, De Boelelaan 1117, 1081 HV Amsterdam, Netherlands.
4Centre for Neuroscience and Trauma, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Robert A. Harris
1Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden.
Tomas Olsson
1Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden.
Maja Jagodic
1Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden.
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