Unresponsiveness to inhaled antigen is governed by conventional dendritic cells and overridden during infection by monocytes

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Science Immunology  09 Oct 2020:
Vol. 5, Issue 52, eabb5439
DOI: 10.1126/sciimmunol.abb5439

Article Information

vol. 5 no. 52

Published By: 
  • Received March 2, 2020
  • Accepted September 17, 2020
  • .

Author Information

  1. James G. Bedford1,
  2. Melanie Heinlein2,3,
  3. Alexandra L. Garnham2,3,
  4. Thi H. O. Nguyen1,
  5. Tom Loudovaris4,
  6. Chenghao Ge1,5,
  7. Stuart I. Mannering4,
  8. Michael Elliott6,7,
  9. Stuart G. Tangye8,9,
  10. Katherine Kedzierska1,
  11. Daniel H. D. Gray2,3,
  12. William R. Heath1 and
  13. Linda M. Wakim1,*
  1. 1Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.
  2. 2Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.
  3. 3Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.
  4. 4Immunology and Diabetes Unit, St Vincent’s Institute of Medical Research, Fitzroy, Victoria 3065, Australia.
  5. 5School of Medicine, Tsinghua University, Beijing, China.
  6. 6Sydney Medical School, University of Sydney, Sydney, New South Wales 2006, Australia.
  7. 7Chris O’Brien Lifehouse Cancer Centre, Royal Prince Alfred Hospital, Camperdown, New South Wales 2050, Australia.
  8. 8Immunity & Inflammation Theme, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia.
  9. 9St Vincent’s Clinical School, University of New South Wales, Sydney, New South Wales 2052, Australia.
  1. *Corresponding author. Email: wakiml{at}


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