Research ArticleCORONAVIRUS

Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients

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Science Immunology  08 Oct 2020:
Vol. 5, Issue 52, eabe5511
DOI: 10.1126/sciimmunol.abe5511

Article Information

vol. 5 no. 52

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Published By: 
History: 
  • Received August 28, 2020
  • Accepted October 5, 2020
  • .

Author Information

  1. Baweleta Isho1,,
  2. Kento T. Abe2,3,,
  3. Michelle Zuo1,,
  4. Alainna J. Jamal4,5,,
  5. Bhavisha Rathod2,
  6. Jenny H. Wang2,
  7. Zhijie Li3,
  8. Gary Chao1,
  9. Olga L. Rojas1,
  10. Yeo Myong Bang1,
  11. Annie Pu1,
  12. Natasha Christie-Holmes6,
  13. Christian Gervais7,
  14. Derek Ceccarelli2,
  15. Payman Samavarchi-Tehrani2,
  16. Furkan Guvenc3,
  17. Patrick Budylowski6,8,
  18. Angel Li5,
  19. Aimee Paterson, Resources5,
  20. Feng Yun Yue1,
  21. Lina M. Marin9,
  22. Lauren Caldwell2,
  23. Jeffrey L. Wrana2,3,
  24. Karen Colwill2,
  25. Frank Sicheri2,3,
  26. Samira Mubareka10,
  27. Scott D. Gray-Owen3,6,
  28. Steven J. Drews11,
  29. Walter L. Siqueira9,
  30. Miriam Barrios-Rodiles2,
  31. Mario Ostrowski1,12,13,
  32. James M. Rini3,14,
  33. Yves Durocher7,
  34. Allison J. McGeer2,4,5,
  35. Jennifer L. Gommerman1,* and
  36. Anne-Claude Gingras2,3,*
  1. 1Department of Immunology, University of Toronto, Toronto, ON, Canada.
  2. 2Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital, Sinai Health System, Toronto, ON, Canada.
  3. 3Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
  4. 4Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.
  5. 5Department of Microbiology, at Mount Sinai Hospital, Sinai Health System, Toronto, ON, Canada.
  6. 6Combined Containment Level 3 Unit, University of Toronto, Toronto, ON, Canada.
  7. 7Mammalian Cell Expression, Human Health Therapeutics Research Centre, National Research Council Canada, Montréal, QC, Canada.
  8. 8Institute of Medical Science, University of Toronto, Toronto, ON, Canada.
  9. 9College of Dentistry, University of Saskatchewan, Saskatoon, SK, Canada.
  10. 10Department of Laboratory Medicine and Molecular Diagnostics, Division of Microbiology, Sunnybrook Health Sciences Centre; Biological Sciences, Sunnybrook Research Institute; and Division of Infectious Diseases, Sunnybrook Health Sciences Centre, Toronto, ON, Canada; Department of Laboratory Medicine and Pathology, University of Toronto, Toronto, ON, Canada.
  11. 11Canadian Blood Services, Edmonton, AB & Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada.
  12. 12St. Michael’s Hospital, Toronto, ON, Canada; Li Ka Shing Knowledge Institute.
  13. 13Department of Medicine, University of Toronto, Toronto, ON, Canada.
  14. 14Department of Biochemistry, University of Toronto, Toronto, ON, Canada.
  1. *Correspondence to: jen.gommerman{at}utoronto.ca; gingras{at}lunenfeld.ca
  • These authors contributed equally

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