Research ArticleCELL DEATH Shiga toxin suppresses noncanonical inflammasome responses to cytosolic LPS View ORCID ProfileMorena S. Havira, View ORCID ProfileAtri Ta, View ORCID ProfilePuja Kumari, Chengliang Wang, View ORCID ProfileAshley J. Russo, View ORCID ProfileJianbin Ruan, View ORCID ProfileVijay A. Rathinam and View ORCID ProfileSivapriya Kailasan Vanaja*Department of Immunology, UConn Health School of Medicine, 263 Farmington Ave., Farmington, CT 06030, USA.↵*Corresponding author. Email: kailasanvanaja{at}uchc.edu See allHide authors and affiliations Science Immunology 27 Nov 2020:Vol. 5, Issue 53, eabc0217DOI: 10.1126/sciimmunol.abc0217 Morena S. Havira Department of Immunology, UConn Health School of Medicine, 263 Farmington Ave., Farmington, CT 06030, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Morena S. Havira Atri Ta Department of Immunology, UConn Health School of Medicine, 263 Farmington Ave., Farmington, CT 06030, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Atri Ta Puja Kumari Department of Immunology, UConn Health School of Medicine, 263 Farmington Ave., Farmington, CT 06030, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Puja Kumari Chengliang Wang Department of Immunology, UConn Health School of Medicine, 263 Farmington Ave., Farmington, CT 06030, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Ashley J. Russo Department of Immunology, UConn Health School of Medicine, 263 Farmington Ave., Farmington, CT 06030, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Ashley J. Russo Jianbin Ruan Department of Immunology, UConn Health School of Medicine, 263 Farmington Ave., Farmington, CT 06030, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Jianbin Ruan Vijay A. Rathinam Department of Immunology, UConn Health School of Medicine, 263 Farmington Ave., Farmington, CT 06030, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Vijay A. Rathinam Sivapriya Kailasan Vanaja Department of Immunology, UConn Health School of Medicine, 263 Farmington Ave., Farmington, CT 06030, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Sivapriya Kailasan Vanaja For correspondence: kailasanvanaja@uchc.edu Article Figures & Data Info & Metrics eLetters PDF Article Information vol. 5 no. 53 DOI: https://doi.org/10.1126/sciimmunol.abc0217 PubMed: 33246946 Published By: Science Immunology History: Received April 1, 2020Revision received October 2, 2020Accepted November 6, 2020 . Copyright & Usage: Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works https://www.sciencemag.org/about/science-licenses-journal-article-reuseThis is an article distributed under the terms of the Science Journals Default License. Author Information Morena S. Havira, Atri Ta, Puja Kumari, Chengliang Wang, Ashley J. Russo, Jianbin Ruan, Vijay A. Rathinam and Sivapriya Kailasan Vanaja*Department of Immunology, UConn Health School of Medicine, 263 Farmington Ave., Farmington, CT 06030, USA.↵*Corresponding author. Email: kailasanvanaja{at}uchc.edu Altmetric Article usage Article lifetimeLast 6 monthsThis monthArticle usage: November 2020 to March 2021 AbstractFullPdf Nov 20203548426116 Dec 202025081434322 Jan 2021743278102 Feb 20211882820 Mar 20211310 View Full Text
Shiga toxin suppresses noncanonical inflammasome responses to cytosolic LPS By Morena S. Havira, Atri Ta, Puja Kumari, Chengliang Wang, Ashley J. Russo, Jianbin Ruan, Vijay A. Rathinam, Sivapriya Kailasan Vanaja Science Immunology27 Nov 2020 Shiga toxin, a phage-encoded bacterial virulence factor, inhibits caspase-11–mediated inflammasome responses. Supplementary Materials
Shiga toxin suppresses noncanonical inflammasome responses to cytosolic LPS By Morena S. Havira, Atri Ta, Puja Kumari, Chengliang Wang, Ashley J. Russo, Jianbin Ruan, Vijay A. Rathinam, Sivapriya Kailasan Vanaja Science Immunology27 Nov 2020 Shiga toxin, a phage-encoded bacterial virulence factor, inhibits caspase-11–mediated inflammasome responses. Supplementary Materials