CD4⁺ T cell activation and concomitant mTOR metabolic inhibition can ablate microbiota-specific memory cells and prevent colitis

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  CD4⁺ T cell activation and concomitant mTOR metabolic inhibition can ablate microbiota-specific memory cells and prevent colitis

  By Qing Zhao, Lennard W. Duck, Fengyuan Huang, Katie L. Alexander, Craig L. Maynard, Peter J. Mannon, Charles O. Elson

  Science Immunology11 Dec 2020

  Activation by multi-epitope peptide plus mTOR inhibition depletes flagellin-reactive CD4⁺ T cells and prevents intestinal inflammation.

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  CD4⁺ T cell activation and concomitant mTOR metabolic inhibition can ablate microbiota-specific memory cells and prevent colitis

  By Qing Zhao, Lennard W. Duck, Fengyuan Huang, Katie L. Alexander, Craig L. Maynard, Peter J. Mannon, Charles O. Elson

  Science Immunology11 Dec 2020

  Activation by multi-epitope peptide plus mTOR inhibition depletes flagellin-reactive CD4⁺ T cells and prevents intestinal inflammation.

  • Supplementary Materials

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