March 2021
Vol 6, Issue 57

About The Cover

Cover image expansion

ONLINE COVER Activating Acetylcholine Production. This month's cover shows a section of mouse jejunum prepared 7 days after infection with the helminth parasite Nippostrongylus brasiliensis. Hyperplasia of both yellow goblet cells (stained with the UEA-I lectin) and magenta tuft cells (expressing doublecortin-like kinase 1) is observed as part of the host immune response to this infection. Roberts et al. found that ILC2 synthesis and secretion of the neurotransmitter acetylcholine contributed to effective expulsion of the parasites. [CREDIT: NAVEEN PARMAR/NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY]