Research ArticleINNATE IMMUNITY

Deep-sea microbes as tools to refine the rules of innate immune pattern recognition

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Science Immunology  12 Mar 2021:
Vol. 6, Issue 57, eabe0531
DOI: 10.1126/sciimmunol.abe0531

Article Information

vol. 6 no. 57

PubMed: 
Published By: 
History: 
  • Received July 28, 2020
  • Accepted February 11, 2021
  • .

Author Information

  1. Anna E. Gauthier1,2,3,
  2. Courtney E. Chandler4,
  3. Valentina Poli5,
  4. Francesca M. Gardner4,
  5. Aranteiti Tekiau6,
  6. Richard Smith4,
  7. Kevin S. Bonham7,
  8. Erik E. Cordes8,
  9. Timothy M. Shank9,
  10. Ivan Zanoni5,
  11. David R. Goodlett4,10,
  12. Steven J. Biller7,
  13. Robert K. Ernst4,
  14. Randi D. Rotjan3,* and
  15. Jonathan C. Kagan1,*
  1. 1Division of Gastroenterology, Boston Children’s Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  2. 2Program in Virology, Harvard Medical School, Boston, MA 02115, USA.
  3. 3Department of Biology, Boston University, 5 Cummington Mall, Boston, MA 02215, USA.
  4. 4Department of Microbial Pathogenesis, University of Maryland, Baltimore, 650 W. Baltimore Street, Baltimore, MD 21201, USA.
  5. 5Harvard Medical School, and Boston Children’s Hospital, Division of Immunology, Division of Gastroenterology, Boston, MA 02115, USA.
  6. 6Ministry of Fisheries, Republic of Kiribati, Tarawa, Kiribati.
  7. 7Department of Biological Sciences, Wellesley College, 106 Central St., Wellesley, MA 02481, USA.
  8. 8Department of Biology, Temple University, 1900 N. 12th St., Philadelphia, PA 19122, USA.
  9. 9Biology Department, MS33, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.
  10. 10International Centre for Cancer Vaccine Science, University of Gdansk, Wita Stwosza 63, 80-308 Gdansk, Poland.
  1. *Corresponding author. Email: jonathan.kagan{at}childrens.harvard.edu (J.C.K.); rrotjan{at}bu.edu (R.D.R.)

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