Research ArticleT CELLS

A fetal wave of human type 3 effector γδ cells with restricted TCR diversity persists into adulthood

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Science Immunology  23 Apr 2021:
Vol. 6, Issue 58, eabf0125
DOI: 10.1126/sciimmunol.abf0125

Article Information

vol. 6 no. 58

PubMed: 
Published By: 
History: 
  • Received September 28, 2020
  • Revision received December 17, 2020
  • Accepted March 24, 2021
  • .

Author Information

  1. Likai Tan1,2,,
  2. Alina Suzann Fichtner1,,
  3. Elena Bruni1,
  4. Ivan Odak1,
  5. Inga Sandrock1,
  6. Anja Bubke1,
  7. Alina Borchers3,
  8. Christian Schultze-Florey1,4,
  9. Christian Koenecke1,4,
  10. Reinhold Förster1,5,
  11. Michael Jarek6,
  12. Constantin von Kaisenberg7,
  13. Ansgar Schulz8,
  14. Xiaojing Chu9,10,
  15. Bowen Zhang10,
  16. Yang Li5,10,
  17. Ulf Panzer3,
  18. Christian F. Krebs3,
  19. Sarina Ravens1,5, and
  20. Immo Prinz1,2,5,,*
  1. 1Institute of Immunology, Hannover Medical School (MHH), Hannover, Germany.
  2. 2Institute of Systems Immunology, Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  3. 3Translational Immunology, III. Department of Medicine, Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  4. 4Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
  5. 5Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany.
  6. 6Genome Analytics, Helmholtz Centre for Infection Research, Braunschweig, Germany.
  7. 7Department of Obstetrics, Gynecology, and Reproductive Medicine, Hannover Medical School, Hannover, Germany.
  8. 8Department of Pediatrics, University Medical Center Ulm, Ulm, Germany.
  9. 9Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
  10. 10Department of Computational Biology for Individualised Medicine TWINCORE, Helmholtz Centre for Infection Research and Hannover Medical School, Hannover, Germany.
  1. *Corresponding author. Email: i.prinz{at}uke.de
  • These authors contributed equally to this work.

  • These authors contributed equally to this work.

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