Research ArticleTUMOR IMMUNOLOGY

The AIM2 and NLRP3 inflammasomes trigger IL-1–mediated antitumor effects during radiation

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Science Immunology  07 May 2021:
Vol. 6, Issue 59, eabc6998
DOI: 10.1126/sciimmunol.abc6998

Article Information

vol. 6 no. 59

PubMed: 
Published By: 
History: 
  • Received May 8, 2020
  • Accepted April 6, 2021
  • .

Author Information

  1. Chuanhui Han1,,
  2. Victoria Godfrey1,,
  3. Zhida Liu1,
  4. Yanfei Han2,
  5. Longchao Liu1,
  6. Hua Peng2,
  7. Ralph R. Weichselbaum3,
  8. Hasan Zaki1,* and
  9. Yang-Xin Fu1,*
  1. 1Department of Pathology, UT Southwestern Medical Center, Dallas, TX, USA.
  2. 2Institute of Biophysics, Chinese Academy of Sciences. Beijing, China.
  3. 3Department of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, University of Chicago, Chicago, IL, USA.
  1. *Corresponding author. Email: hasan.zaki{at}utsouthwestern.edu (H.Z.); yang-xin.fu{at}utsouthwestern.edu (Y.-X.F.)
  • These authors contributed equally to this work.

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