Research ArticleINNATE IMMUNITY

Selective Janus kinase inhibition preserves interferon-λ–mediated antiviral responses

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Science Immunology  14 May 2021:
Vol. 6, Issue 59, eabd5318
DOI: 10.1126/sciimmunol.abd5318

Article Information

vol. 6 no. 59

PubMed: 
Published By: 
History: 
  • Received June 29, 2020
  • Revision received December 23, 2020
  • Accepted April 15, 2021
  • .

Author Information

  1. Daniel Schnepf1,2,*,
  2. Stefania Crotta3,
  3. Thiprampai Thamamongood1,2,4,5,
  4. Megan Stanifer6,
  5. Laura Polcik1,
  6. Annette Ohnemus1,
  7. Juliane Vier7,
  8. Celia Jakob1,
  9. Miriam Llorian8,
  10. Hans Henrik Gad9,
  11. Rune Hartmann9,
  12. Birgit Strobl10,
  13. Susanne Kirschnek7,
  14. Steeve Boulant11,
  15. Martin Schwemmle1,5,
  16. Andreas Wack3 and
  17. Peter Staeheli1,5,*
  1. 1Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany.
  2. 2Spemann Graduate School of Biology and Medicine, Albert Ludwigs University Freiburg, Freiburg, Germany.
  3. 3Immunoregulation Laboratory, The Francis Crick Institute, London, UK.
  4. 4Faculty of Biology, University of Freiburg, Freiburg, Germany.
  5. 5Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  6. 6Department of Infectious Diseases, Molecular Virology, Heidelberg University, Heidelberg, Germany.
  7. 7Faculty of Medicine, Institute of Medical Microbiology and Hygiene, Medical Center University of Freiburg, Freiburg, Germany.
  8. 8Bioinformatics and Biostatistics, The Francis Crick Institute, London, UK.
  9. 9Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
  10. 10Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, Austria.
  11. 11Department of Infectious Diseases, Virology, Heidelberg University, Heidelberg, Germany.
  1. *Corresponding author. Email: daniel.schnepf{at}uniklinik-freiburg.de (D.S.); peter.staeheli{at}uniklinik-freiburg.de (P.S.)

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