Research ArticleMUCOSAL IMMUNOLOGY

IL-1R1–dependent signaling coordinates epithelial regeneration in response to intestinal damage

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Science Immunology  07 May 2021:
Vol. 6, Issue 59, eabe8856
DOI: 10.1126/sciimmunol.abe8856

Article Information

vol. 6 no. 59

PubMed: 
Published By: 
History: 
  • Received September 21, 2020
  • Accepted April 8, 2021
  • .

Author Information

  1. Christian B. Cox1,,
  2. Elaine E. Storm2,,
  3. Varun N. Kapoor3,
  4. Joseph Chavarria-Smith1,
  5. David L. Lin1,
  6. Lifen Wang1,
  7. Yun Li1,
  8. Noelyn Kljavin2,
  9. Naruhisa Ota1,
  10. Travis W. Bainbridge4,
  11. Keith Anderson5,
  12. Merone Roose-Girma5,
  13. Søren Warming5,
  14. Joseph R. Arron1,
  15. Shannon J. Turley3,
  16. Frederic J. de Sauvage2,* and
  17. Menno van Lookeren Campagne1,*,
  1. 1Department of Immunology, Genentech Inc., South San Francisco, CA 94080, USA.
  2. 2Department of Molecular Oncology, Genentech Inc., South San Francisco, CA 94080, USA.
  3. 3Department of Cancer Immunology, Genentech Inc., South San Francisco, CA 94080, USA.
  4. 4Department of Protein Chemistry, Genentech Inc., South San Francisco, CA 94080, USA.
  5. 5Department of Molecular Biology, Genentech Inc., South San Francisco, CA 94080, USA.
  1. *Corresponding author. Email: desauvage.fred{at}gene.com (F.J.d.S.); mennocampagne{at}gmail.com (M.v.L.C.)
  • These authors contributed equally to this work.

  • Present address: Department of Inflammation and Oncology, Amgen Research, Amgen Inc., South San Francisco, CA 94080, USA.

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