Science Immunology

Supplementary Materials

Supplementary Material for:

Arc/Arg3.1 governs inflammatory dendritic cell migration from the skin and thereby controls T cell activation

Friederike Ufer, Pablo Vargas, Jan Broder Engler, Joseph Tintelnot, Benjamin Schattling, Hana Winkler, Simone Bauer, Nina Kursawe, Anne Willing, Oliver Keminer, Ora Ohana, Gabriela Salinas-Riester, Ole Pless, Dietmar Kuhl, Manuel A. Friese*

*Corresponding author. Email: manuel.friese{at}

Published 23 September 2016, Sci. Immunol. 1, eaaf8665 (2016)
DOI: 10.1126/sciimmunol.aaf8665

This PDF file includes:

  • Fig. S1. Arc/Arg3.1 is expressed in various migDC subsets.
  • Fig. S2. Unaltered immune cells and progenitors in Arc/Arg3.1−/− mice.
  • Fig. S3. Arc/Arg3.1 does not influence antigen uptake, maturation, or calcium signaling in DCs.
  • Fig. S4. Normal distribution of integrins in the absence of Arc/Arg3.1.
  • Fig. S5. Arc/Arg3.1 is not induced by DC stimulation and has no influence on cofilin phosphorylation.
  • Fig. S6. Ameliorated EAE disease course but normal T cell stimulation in the absence of Arc/Arg3.1.
  • Fig. S7. Graphical summary of our findings.
  • Fig. S8. Uncropped immunoblots.
  • Fig. S9. Flow cytometry gating strategies.

Download PDF

Other Supplementary Material for this manuscript includes the following:

  • Table S1. BMDC microarray data.
  • Table S2. Exact values.

Download Tables S1 and S2

Files in this Data Supplement: