Science Immunology
Supplementary Materials
Arc/Arg3.1 governs inflammatory dendritic cell migration from the skin and thereby controls T cell activation
Friederike Ufer, Pablo Vargas, Jan Broder Engler, Joseph Tintelnot, Benjamin Schattling, Hana Winkler, Simone Bauer, Nina Kursawe, Anne Willing, Oliver Keminer, Ora Ohana, Gabriela Salinas-Riester, Ole Pless, Dietmar Kuhl, Manuel A. Friese*
*Corresponding author. Email: manuel.friese{at}zmnh.uni-hamburg.de
Published 23 September 2016, Sci. Immunol. 1, eaaf8665 (2016)
DOI: 10.1126/sciimmunol.aaf8665
This PDF file includes:
- Fig. S1. Arc/Arg3.1 is expressed in various migDC subsets.
- Fig. S2. Unaltered immune cells and progenitors in Arc/Arg3.1−/− mice.
- Fig. S3. Arc/Arg3.1 does not influence antigen uptake, maturation, or calcium signaling in DCs.
- Fig. S4. Normal distribution of integrins in the absence of Arc/Arg3.1.
- Fig. S5. Arc/Arg3.1 is not induced by DC stimulation and has no influence on cofilin phosphorylation.
- Fig. S6. Ameliorated EAE disease course but normal T cell stimulation in the absence of Arc/Arg3.1.
- Fig. S7. Graphical summary of our findings.
- Fig. S8. Uncropped immunoblots.
- Fig. S9. Flow cytometry gating strategies.
Other Supplementary Material for this manuscript includes the following:
- Table S1. BMDC microarray data.
- Table S2. Exact values.
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