Science Immunology
Supplementary Materials
Supplementary Material for:
Type I interferon suppresses virus-specific B cell responses by modulating CD8+ T cell differentiation
E. Ashley Moseman, Tuoqi Wu, Juan Carlos de la Torre, Pamela L. Schwartzberg, Dorian B. McGavern*
*Corresponding author. Email: mcgavernd{at}mail.nih.gov
Published 21 October 2016, Sci. Immunol. 1, eaah3565 (2016)
DOI: 10.1126/sciimmunol.aah3565
This PDF file includes:
- Materials and Methods
- Fig. S1. Effects of IFNAR blockade and virus strain or titer on LCMV-specific B cells.
- Fig. S2. CTL engagement of antiviral B cells and control LCMV-iCre–infected Confetti mice.
- Legends for movies S1 to S6
- References (66–72)
Other Supplementary Material for this manuscript includes the following:
- Movie S1 (.mov format). LCMV-specific B cells thrive upon late transfer into infected hosts.
- Movie S2 (.mov format). IFNAR blockade prevents deletion of LCMV-specific B cells.
- Movie S3 (.mov format). LCMV-specific CTLs flux calcium upon contact with LCMV-specific B cells.
- Movie S4 (.mov format). Antiviral CTLs productively engage LCMV-specific B cells.
- Movie S5 (.mov format). LCMV-specific B cells are killed in vivo.
- Movie S6 (.mov format). LCMV-infected B cells contribute to clonal GCs in the absence of functional CTLs.
- Table S1 (Microsoft excel format). Excel file containing tabulated data for Figs. 1 to 7 and fig. S1.
Files in this Data Supplement: