Science Immunology

Supplementary Materials

Supplementary Material for:

Tracking the fate and origin of clinically relevant adoptively transferred CD8+ T cells in vivo

Aude G. Chapuis,* Cindy Desmarais, Ryan Emerson, Thomas M. Schmitt, Kendall C. Shibuya, Ivy P. Lai, Felecia Wagener, Jeffrey Chou, Ilana M. Roberts, David G. Coffey, Edus H. Warren, Harlan Robins, Philip D. Greenberg, Cassian Yee*

*Corresponding author. Email: achapuis{at}fredhutch.org (A.G.C.); cyee{at}mdanderson.org (C.Y.)

Published 24 February 2017, Sci. Immunol. 2, eaal2568 (2017)
DOI: 10.1126/sciimmunol.aal2568

This PDF file includes:

  • Fig. S1. Na├»ve versus antigen-experienced phenotype based on clonotype frequency in PBMCs.
  • Table S1. Total, productive, and unique sequences in each sample.
  • Table S2. Identical results obtained by standard PCR and HTTCS for infused monoclonal products.
  • Table S3. Clonotype composition of monoclonal and polyclonal CTL products.
  • Table S4. Clinical responses of patients with metastatic melanoma who received polyclonal CTL products.
  • Table S5. Ki67 expression of transferred multimer+ CTLs in patients who achieved CRs.

Download PDF

Files in this Data Supplement: