Science Immunology

Supplementary Materials

Supplementary Material for:

Resident memory CD8+ T cells in the upper respiratory tract prevent pulmonary influenza virus infection

Angela Pizzolla, Thi H. O. Nguyen, Jeffrey M. Smith, Andrew G. Brooks, Katherine Kedzierska, William R. Heath, Patrick C. Reading, Linda M. Wakim*

*Corresponding author. Email: wakiml{at}unimelb.edu.au

Published 2 June 2017, Sci. Immunol. 2, eaam6970 (2017)
DOI: 10.1126/sciimmunol.eaam6970

This PDF file includes:

  • Fig. S1. Lung and nasal tissue Trm cells develop from KLRG1 precursor cells.
  • Fig. S2. Molecular signature of nasal tissue Trm cells.
  • Fig. S3. Localization of NP, PA, and PB1 CD103+CD69+ Trm cells in the lung after influenza virus infection.
  • Fig. S4. Trm cell development after dendritic cell immunization.
  • Fig. S5. Depletion of CD8 T cells eliminates local protection in the nasal tissue after influenza virus rechallenge.
  • Fig. S6. Gating strategy for identifying transgenic OT-I in spleen, lung, and nasal tissue of influenza virus–infected mice.
  • Fig. S7. Gating strategy for identifying endogenous influenza virus–specific CD8+ T cells in spleen, lung, and nasal tissue of influenza virus–infected mice.

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Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). Source data file.

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