Science Immunology

Supplementary Materials

Supplementary Material for:

An immune clock of human pregnancy

Nima Aghaeepour, Edward A. Ganio, David Mcilwain, Amy S. Tsai, Martha Tingle, Sofie Van Gassen, Dyani K. Gaudilliere, Quentin Baca, Leslie McNeil, Robin Okada, Mohammad S. Ghaemi, David Furman, Ronald J. Wong, Virginia D. Winn, Maurice L. Druzin, Yaser Y. El-Sayed, Cecele Quaintance, Ronald Gibbs, Gary L. Darmstadt, Gary M. Shaw, David K. Stevenson, Robert Tibshirani, Garry P. Nolan, David B. Lewis, Martin S. Angst, Brice Gaudilliere*

*Corresponding author. Email:

Published 1 September 2017, Sci. Immunol. 2, eaan2946 (2017)
DOI: 10.1126/sciimmunol.aan2946

This PDF file includes:

  • Materials and Methods
  • Fig. S1. Gating strategy of immune cell subsets.
  • Fig. S2. Reduced csEN model components.
  • Fig. S3. Time-dependent changes in csEN model components are reflected across communities of interrelated immune features.
  • Table S1. Antibody panel used for mass cytometry analysis.
  • Table S2. Signaling responses prioritized in the signaling-based penalization matrix by a 5:1 margin.
  • Table S3. Features excluded from the csEN model as compared with the non? signaling-based EN model.
  • Table S4. Reduced csEN model components.
  • References (40–49)

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