Supplementary Material for:

Dynamics of the human antibody repertoire after B cell depletion in systemic sclerosis

Charles F. A. de Bourcy, Cornelia L. Dekker, Mark M. Davis, Mark R. Nicolls, Stephen R. Quake*

*Corresponding author. Email: quake{at}stanford.edu

Published 29 September 2017, Sci. Immunol. 2, eaan8289 (2017)
DOI: 10.1126/sciimmunol.aan8289

This PDF file includes:

• Materials and Methods
• Fig. S1. Comparison of healthy and SSc-PAH cohorts at baseline.
• Fig. S2. Calculation of rates governing repertoire homeostasis.
• Fig. S3. Assessment of repertoire elasticity under depletion.
• Table S1. Data values displayed in Fig. 1E.
• Table S2. Data values displayed in Fig. 1F.
• Table S3. Data values displayed in Fig. 4A.
• Table S4. Data values displayed in Fig. 4C.
• Table S5. Data values displayed in Fig. 4D.
• Table S6. Repertoire isotype percentages for each participant and time point (longitudinal experiment).
• Table S7. IGH constant-region primer pool.
• Table S8. IGH variable-region primer pool.
• Table S9. Read counts before and after processing.
• Table S10. Data values displayed in fig. S2A.
• Table S11. Data values displayed in fig. S2B.
• Table S12. Data values displayed in fig. S2D.
• References (44–46)

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