Science Immunology

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Supplementary Material for:

Mitochondria maintain controlled activation state of epithelial-resident T lymphocytes

Špela Konjar, Ulrika C. Frising, Cristina Ferreira, Reinhard Hinterleitner, Toufic Mayassi, Qifeng Zhang, Birte Blankenhaus, Nejc Haberman, Yunhua Loo, Joana Guedes, Marta Baptista, Silvia Innocentin, Joerg Stange, Douglas Strathdee, Bana Jabri, Marc Veldhoen*

*Corresponding author. Email: marc.veldhoen{at}

Published 22 June 2018, Sci. Immunol. 3, eaan2543 (2018)
DOI: 10.1126/sciimmunol.aan2543

This PDF file includes:

  • Fig. S1. IELs are a homogeneous population based on surface activation markers.
  • Fig. S2. LAMP-1 staining in CD8+ T cells.
  • Fig. S3. IELs are maintained and contain increased numbers of mitochondria.
  • Fig. S4. IELs have altered mitochondrial staining.
  • Fig. S5. IEL mitochondrial staining correlates with activation.
  • Fig. S6. IEL mitochondria have altered CL composition.
  • Fig. S7. CL species distribution in T lymphocytes.
  • Fig. S8. Tafazzin is important in IEL activation.
  • Table S1. Characteristics of IELs compared with naive, effector, and memory CD8+</su T cells.

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