Science Immunology

Supplementary Materials

The PDF file includes:

  • Materials and Methods
  • Fig. S1. Expression and validation of hpMR1.
  • Fig. S2. hpMR1 tetramer staining of MAIT cell clones.
  • Fig. S3. MR1T clone responses to 5-OP-RU in tetraSPOT assay with MR1/5-OP-RU.
  • Fig. S4. Raw LC-MS data for previously identified ligands 5-OP-RU/rRL-6-CH2OH and RL-6-Me-7-OH.
  • Fig. S5. Raw MS2 fragment spectra for acetyl RL-6-Me-7-OH and riboflavin adducts.
  • Fig. S6. Raw LC-MS data for newly described MR1 ligands riboflavin, FO, PLI, and PLIII.
  • Fig. S7. LC-MS, MS2, and MR1T activation data for hesperidin.
  • Fig. S8. Chemical synthesis pathway for FO, PLI, and PLIII.
  • References (3335)

Download PDF

Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). Tabulated raw data.

Files in this Data Supplement: