Science Immunology

Supplementary Materials

The PDF file includes:

  • Methods
  • Fig. S1. In response to subunit vaccination, the formation of T cell memory is substantially reduced in an IL-15−/− host.
  • Fig. S2. IL-15 is required to support survival of vaccine-elicited T cells, not for their initial expansion to antigenic challenge.
  • Fig. S3. Vaccine-elicited T cells express levels of IRF4 substantially higher than in T cells responding to viral challenge.
  • Fig. S4. Vaccine- and infection-elicited T cells express both overlapping and unique gene sets when compared with naïve T cells.
  • Fig. S5. Vaccine-elicited T cells express predominantly a central memory phenotype as compared with T cells responding to infection.
  • Fig. S6. Global gene expression differences and representative gene sets in WT versus IL-27R−/− T cells responding to subunit vaccination.
  • Fig. S7. Tbet expression in vaccine-elicited T cells from WT mice is elevated compared with WT T cells responding to virus infection.
  • References (6674)

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Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). Raw data.

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