Science Immunology

Supplementary Materials

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  • Materials and Methods
  • Fig. S1. Identification of Bb as Treg-inducing bacteria.
  • Fig. S2. Effect of Bb monocolonization on cytokine levels in Treg and non-Treg cells.
  • Fig. S3. Bb monocolonization facilitates de novo generation of pTreg cells.
  • Fig. S4. Bb colonization induces dietary Ag– and/or microbiota-reactive Treg cells.
  • Fig. S5. Effect of Bb monocolonization on the TCR repertoire of Treg cells.
  • Fig. S6. Effect of Bb monocolonization on phenotypes and population of cLP-DC subtypes.
  • Fig. S7. Effect of Bb monocolonization on phenotypes and population of DC subtypes in mLN and siLP.
  • Fig. S8. CSGG of the Bb enhances Treg cell induction.
  • Fig. S9. Role of DC subtypes in inducing Bb/CSGG-mediated iTreg cells.
  • Fig. S10. CSGG facilitates iTreg induction through TLR2-mediated generation of regulatory DCs.
  • Fig. S11. CSGG-induced iTreg cells are capable of suppressing intestinal inflammation.
  • Fig. S12. Confirmation of Bf monocolonization by DNA sequencing.
  • Table S1. Peptide sequences of α-chain CDR3 region of Treg cells sorted from colon, mLN, and spleen of Bb-monocolonized mice compared with GF mice.
  • Table S2. Peptide sequences of β-chain CDR3 region of Treg cells sorted from colon, mLN, and spleen of Bb-monocolonized mice compared with GF mice.
  • References (4955)

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