Science Immunology

Supplementary Materials

The PDF file includes:

  • Fig. S1. Human skin-resident Treg expression of TH17-associated genes.
  • Fig. S2. CD27 and OX40 coexpression on Tregs.
  • Fig. S3. Deletion of CD27 or OX40 on Tregs results in increased IL-17 expression in vitro.
  • Fig. S4. CD27 signaling suppresses Treg expression of TH17-associated genes.
  • Fig. S5. OX40 is important for Treg accumulation in adoptive transfer model before C. albicans infection.
  • Fig. S6. Deletion of either CD27 or OX40 in Tregs has minimal effect on skin inflammation.
  • Fig. S7. OX40 is preferentially expressed on Tregs in healthy human skin.
  • Fig. S8. Percentages and MFI of FOXP3 in Tregs in human disease.
  • Fig. S9. Gating strategy for murine and human Tregs and Teffs.
  • Table S1. Effects of CD27 engagement on TH17 cytokines.
  • Table S2. Effects of CD27 engagement on signature Treg genes.
  • Table S3. Antibodies.

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Other Supplementary Material for this manuscript includes the following:

  • Table S4 (Microsoft Excel format). Raw data.

Files in this Data Supplement: