Science Immunology

Supplementary Materials

The PDF file includes:

  • Fig. S1. Identification of human TH cell subsets by chemokine receptor expression.
  • Fig. S2. Activation-dependent expression of cytokines in TH2 clones.
  • Fig. S3. Cytokine profile after reactivation of in vitro–primed “TH9” cells.
  • Fig. S4. Correlation values of all genes with IL-9 in TH1, TH2, and IL-9+ TH2 clones.
  • Fig. S5. PPARG levels during first and second rounds of in vitro priming of naïve TH cells.
  • Fig. S6. IL-7Rα and CRLF2 form a functional TSLP-R on IL-9+ TH2 cells.
  • Fig. S7. IL-6Rα is highly expressed on IL-9+ TH2 cells, and IL-6 promotes IL-9 expression in polarizing “TH9” cells.
  • Fig. S8. Effect of PPAR-γ inhibition by GW9662 or RNA interference on cytokine production in human TH cells.
  • Fig. S9. PPAR-γ agonists do not promote IL-9 or TH2 cytokine expression in IL-9+ TH2 cells.
  • Fig. S10. Cytokine profiles of TH cells from human inflammatory skin disease.
  • Fig. S11. PPAR-γ immunohistochemistry in AD and aACD and PPAR-γ antagonism in skin TH cell lines.
  • Fig. S12. Gating strategies for flow cytometry analysis.
  • Legend for table S1
  • Table S2. Antibodies used in this study.
  • Table S3. RT-PCR primers used in this study.

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Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). Raw data file.

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