Science Immunology

Supplementary Materials

The PDF file includes:

  • Fig. S1. Age of NET participants at time of serum sample collection.
  • Fig. S2. Sex effects on ACAb responses in CD (n = 32) and HC (n = 90) serum samples from NET participants.
  • Fig. S3. Sex effects on ACAb responses in T1D (n = 49) and HC (n = 90) serum samples from NET participants.
  • Fig. S4. Age of TrialNet participants at time of serum sample collection.
  • Fig. S5. Follow-up period and time of serum sample collection from TrialNet participants.
  • Fig. S6. ACAb responses in serum samples from TrialNet participants.
  • Fig. S7. All ACAb responses, separated by HLA haplotype and clinical status in TrialNet serum samples.
  • Fig. S8. ACAb responses displaying interaction effects between HLA haplotype and clinical status in TrialNet serum samples.
  • Fig. S9. Correlation between anti-commensal Ig and IgA, IgG1, and IgG2 response indices against MET-2 and R. faecis in TrialNet serum samples.
  • Fig. S10. HLA dependence of anti-GAD65 and anti-insulin seropositivity in TrialNet serum samples.
  • Fig. S11. ACAb responses associated with islet autoantibody-positive status in TrialNet case samples (n = 68).
  • Table S1. List of bacterial strain pools used in this study.

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