Science Immunology

Supplementary Materials

The PDF file includes:

  • Fig. S1. IM-CKV063 in combination with CHK-166 reduces clinical disease and viral RNA.
  • Fig. S2. Viral burden in contralateral ankle with anti-CHIKV mAb therapy.
  • Fig. S3. Gating scheme for infiltrating immune cells in WT mice.
  • Fig. S4. Similar levels of cellular infiltration in the ipsilateral feet at 7 dpi.
  • Fig. S5. Fc effector functions of antibody affect proinflammatory cytokine and chemokine expression.
  • Fig. S6. Gating scheme for infiltrating immune cells in FcRγ−/− and C1q−/− mice.
  • Fig. S7. NK cell depletion does not affect mAb-mediated protection.
  • Table S1. Proinflammatory chemokine and cytokine expression in joint tissue homogenates.

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Other Supplementary Material for this manuscript includes the following:

  • Table S2 (Microsoft Excel file). Raw data in Excel file.

Files in this Data Supplement: