Science Immunology

Supplementary Materials

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  • Fig. S1. Necroptotic cells extend the survival of tumor-bearing mice.
  • Fig. S2. BATF3+ and CD8+ leukocyte requirements for tumor control by necroptotic cells.
  • Fig. S3. DAMP-independent tumor control by necroptotic cells is recapitulated in multiple syngeneic tumor models.
  • Fig. S4. Gating strategies and quantification of T cell subsets in tumor and tdLN after dying cell administration.
  • Fig. S5. Gating strategies and effects of dying cell administration on tumor APC subsets.
  • Fig. S6. Characterization of transduction efficiency and cell death induction by engineered AAVs.
  • Fig. S7. Tumor growth restriction and survival extension after administration of AAVs targeting tumor cell necroptosis in situ.

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