Science Immunology

Supplementary Materials

The PDF file includes:

  • Fig. S1. BP measurements after hypertension induction in mice.
  • Fig. S2. Schematic diagram for RIP-mOVA mice diabetes study.
  • Fig. S3. ConA-induced hepatitis model.
  • Fig. S4. TCR sensitivity is not altered after hypertension.
  • Fig. S5. The phenotypes of hypertensive DCs.
  • Fig. S6. Proinflammatory cytokines produced by hypertensive APCs.
  • Fig. S7. Expression of CD86 and CD80.
  • Fig. S8. Calcium influx under ATP stimulation.
  • Fig. S9. ROS and PGE2 production by DCs after 3 μM ATP treatment.
  • Fig. S10. ATP-induced impermeable dye (YO-PRO-1) uptake and apoptosis.
  • Fig. S11. ATP inhibition and APC surface CD86.
  • Fig. S12. P2X7-deficient DC transfer.
  • Fig. S13. Hypertension induction in the presence of P2X7 antagonist.
  • Fig. S14. Gating strategies of flow cytometry analyses.
  • Table S1. The characteristics of hypertensive patients and normotensive controls.
  • Table S2. The characteristics of normotensive people (NTN), hypertensive patients with BP not well controlled (HTN), and hypertensive patients with BP controlled within normal levels (C-HTN).
  • Table S3. Multivariate linear regressions between plasma ATP and SBP.
  • Table S4. Multivariate linear regressions between plasma ATP and DBP.

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Other Supplementary Material for this manuscript includes the following:

  • Table S5 (Microsoft Excel format). Raw data file.

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