Science Immunology

This PDF file includes:

• Fig. S1. scRNAseq of lung T_regs and comparison with skin T_regs.
• Fig. S2. T_H2-associated chemokine and cytokine receptors are preferentially enriched in skin T_regs compared with lung T_regs.
• Fig. S3. T_H2 cells are enriched in skin.
• Fig. S4. Quantification of cell subsets in the FoxP3^DTR+/+ mice after DT administration.
• Fig. S5. Gating strategy for dermal fibroblasts.
• Fig. S6. T_regs are reduced in skin after DT administration in FoxP3^DTR+/− mice.
• Fig. S7. Immune phenotyping of skin T_regs after Gata3 deletion.
• Fig. S8. No significant differences in neutrophils and inflammatory macrophages after Gata3 deletion in T_regs.
• Fig. S9. No evidence of lung fibrosis after subcutaneous bleomycin injection and Gata3 deletion in T_regs.
• Fig. S10. Blockade of T_H2 cytokines partially rescues fibrosis observed in mice with inducible deletion of Gata3 in T_regs.

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Other Supplementary Material for this manuscript includes the following:

• Table S1. Raw data Excel file.