Science Immunology

Supplementary Materials

This PDF file includes:

  • Fig. S1. scRNAseq of lung Tregs and comparison with skin Tregs.
  • Fig. S2. TH2-associated chemokine and cytokine receptors are preferentially enriched in skin Tregs compared with lung Tregs.
  • Fig. S3. TH2 cells are enriched in skin.
  • Fig. S4. Quantification of cell subsets in the FoxP3DTR+/+ mice after DT administration.
  • Fig. S5. Gating strategy for dermal fibroblasts.
  • Fig. S6. Tregs are reduced in skin after DT administration in FoxP3DTR+/− mice.
  • Fig. S7. Immune phenotyping of skin Tregs after Gata3 deletion.
  • Fig. S8. No significant differences in neutrophils and inflammatory macrophages after Gata3 deletion in Tregs.
  • Fig. S9. No evidence of lung fibrosis after subcutaneous bleomycin injection and Gata3 deletion in Tregs.
  • Fig. S10. Blockade of TH2 cytokines partially rescues fibrosis observed in mice with inducible deletion of Gata3 in Tregs.

Download PDF

Other Supplementary Material for this manuscript includes the following:

Files in this Data Supplement: