Science Immunology

Supplementary Materials

This PDF file includes:

  • Fig. S1. Bioinformatics workflow for whole lung RNA-seq analysis.
  • Fig. S2. Quantification and phenotype of lung γδ T cells 3 days after IAV infection.
  • Fig. S3. RNA-seq bioinformatics of sorted lung γδ T cells 3 days after IAV infection.
  • Fig. S4. Transcriptomic signature of KD-specific genes in lung γδ T cells 3 days after IAV infection.
  • Fig. S5. γδ T cells expansion precedes IAV infection.
  • Fig. S6. Inflammatory myeloid cell infiltration is not affected by KD or HFD.
  • Fig. S7. Proliferation and recruitment drive KD-mediated γδ T cell expansion.
  • Fig. S8. Bioinformatics workflow for whole lung RNA-seq analysis in Mx1 Tcrd−/− mice.
  • Fig. S9. γδ T cell–dependent regulation of KD-induced transcriptome changes.
  • Table S1. Significantly regulated pathways in whole lungs of chow versus KD mice 3 days after IAV infection.
  • Table S2. Gene set enrichment analysis of sorted lung γδ T cells from HFD-fed versus KD-fed mice.
  • Table S3. Gene set enrichment analysis of sorted lung γδ T cells from HFD-fed versus chow-fed mice.
  • Table S4. Gene set enrichment analysis of sorted lung γδ T cells from KD-fed versus chow-fed mice.
  • Table S5. KD-specific gene signature of lung γδ T cells.
  • Table S6. Significantly regulated pathways in whole lungs of Mx1 KD versus Mx1 Tcrd−/− KD mice 3 days after IAV infection.

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