Science Immunology

Supplementary Materials

This PDF file includes:

  • Fig. S1. Full heatmap data for Fig. 3C.
  • Fig. S2. GO and KEGG pathway enrichment analysis in MAIT cell development.
  • Fig. S3. Trajectory analysis on sorted single cells.
  • Fig. S4. MD profiles of DEGs of Lef1+ stage 3 MAIT cells compared with other subsets.
  • Fig. S5. Conventional TCRβ+, NKT, and γδT cell compartments in SAP, Satb1m1Anu/m1Anu, SKG, Cxcr6 KO, and Ccr7 KO mice.
  • Fig. S6. Abnormal Foxp3+ Treg phenotype of mice homozygous for the Satb1m1Anu allele.
  • Fig. S7. MAIT cell development appears to be normal in Bach2-deficient mice.
  • Fig. S8. Full heatmap data for Fig. 5.
  • Fig. S9. DEGs between bulk splenic and thymic mature MAIT cells.
  • Fig. S10. Flow cytometry gating strategies and representative sorting purities.
  • Table S1. Full list of DEGs from bulk (100 cells) purified thymic stage 3 versus stage 1 mouse MAIT cells.
  • Table S2. Full list of top DEGs between stage 3 and stage 1 human MAIT cells.
  • Table S3. List of antibodies used.

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