Science Immunology

Supplementary Materials

The PDF file includes:

  • Fig. S1. Chronic HDM exposure induces PC accumulation in the BM.
  • Fig. S2. Generation and characterization of IgEVenus/Blimp-1mCherry reporter mice.
  • Fig. S3. IgE persists in HDM-exposed mice during rest.
  • Fig. S4. IgE+ PCs are detected in the lung but not the spleen of mice exposed to HDM for 15 weeks and rested for 8 months.
  • Fig. S5. IgE generated after chronic HDM exposure can drive systemic anaphylaxis.
  • Fig. S6. Characterization of allergic and nonallergic donors.
  • Fig. S7. Validation of FcεRIα humanized mice.
  • Fig. S8. Summary model.
  • Table S1. Sγ1 switch region sequence alignment of IgE+ clones from spleen of 4-week HDM-exposed mice and BM of 15-week HDM-exposed mice.
  • Table S2. Mouse antibodies used in the study.
  • Table S3. Human antibodies used in the study.

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Other Supplementary Material for this manuscript includes the following:

  • Data file S1 (Microsoft Excel format). Raw data in Excel spreadsheet.

Files in this Data Supplement: