Science Immunology

Supplementary Materials

The PDF file includes:

  • Fig. S1. Expansion of CD11b+Gr1+ cells during tumor progression in PyMT mice.
  • Fig. S2. MDSCs emerge predominantly in spleen of tumor-bearing mice.
  • Fig. S3. Sample labels and marker genes from scRNAseq analysis.
  • Fig. S4. CD84 is a generalizable MDSC marker in different breast cancer models.
  • Fig. S5. CD84 and JAML are up-regulated by in vitro–generated mouse and human MDSCs.
  • Fig. S6. Characterization and validation of myeloid cell subsets for CD84 and JAML expression.
  • Fig. S7. Reconstruction of MDSC differentiation trajectory in neutrophils and monocytes.
  • Legends for tables S1 to S10

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Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). Marker genes from combined Seurat analysis.
  • Table S2 (Microsoft Excel format). Marker genes from Seurat analysis of monocytes only.
  • Table S3 (Microsoft Excel format). Gene signature from G-MDSCs-versus-neutrophils comparison.
  • Table S4 (Microsoft Excel format). Gene signature from M-MDSCs-versus-monocytes comparison.
  • Table S5 (Microsoft Excel format). Combined MDSC signature gene list.
  • Table S6 (Microsoft Excel format). GO terms (Biological Process 2018) MDSC gene signature.
  • Table S7 (Microsoft Excel format). qPCR primer sequences.
  • Table S8 (Microsoft Excel format). Marker genes from Seurat analysis of neutrophils only.
  • Table S9 (Microsoft Excel format). Neutrophil-specific Monocle state marker genes.
  • Table S10 (Microsoft Excel format). Monocyte-specific Monocle state marker genes.

Files in this Data Supplement: