Science Immunology

Supplementary Materials

The PDF file includes:

  • Methods
  • Fig. S1. Healthy humans make stool IgA but not serum IgE against food antigens.
  • Fig. S2. Daily exposure to food induces minimal food antigen–reactive IgA.
  • Fig. S3. Specific IgA, IgG, IgM, and IgE to peanut are present in the serum of mice exposed to peanut and CT.
  • Fig. S4. Exposure of mice to peanut and CT does not increase TFH cell numbers in MLNs and PPs.
  • Fig. S5. TFH but not Treg or TH17 cells were decreased in MLNs and PPs of T-Bcl6−/− mice.
  • Fig. S6. GC B cells are almost absent in T-Bcl6−/− mice.
  • Fig. S7. IgA+ B cells can be found colocalizing with T cells outside GCs.
  • Fig. S8. IgG1+ but not IgA+ plasmablasts are reduced in T-Bcl6−/− mice.
  • Fig. S9. TFR cell numbers are reduced in PP but not MLN after peanut and CT exposure.
  • Fig. S10. Model of cross-reactive and specific gut IgA induction to peanut.

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Other Supplementary Material for this manuscript includes the following:

  • Table S1. Raw data (Excel spreadsheet).

Files in this Data Supplement: