Science Immunology

Supplementary Materials

The PDF file includes:

  • Materials and Methods
  • Fig. S1. GPR15 expression in TH1/TH2/TH17/Treg/CD8+ T cells from SI or spleen (related to Fig. 1).
  • Fig. S2. Dietary effects of Ahr ligand on GPR15 expression in TH1/TH2/TH17/Treg/CD8+ T cells (related to Fig. 1).
  • Fig. S3. Foxp3 interacts with Ahr to regulate GPR15 expression (related to Fig. 3).
  • Fig. S4. RORγt antagonizes Ahr for DNA binding at the Gpr15 locus (related to Fig. 5).
  • Fig. S5. Ahr promotes gut homing of Tregs by regulating GPR15 (related to Fig. 6).
  • Fig. S6. Human Tregs express GPR15 and other Ahr target genes (related to Fig. 7).
  • Fig. S7. A working model of Ahr-Foxp3-RORγt axis in controlling CD4+ T cell gut homing receptor GPR15.
  • Table S1. Primers for real-time RT-PCR and ChIP assays.

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Other Supplementary Material for this manuscript includes the following:

  • Table S2 (Microsoft Excel format). Raw data for all figures.

Files in this Data Supplement: