Science Immunology

Supplementary Materials

The PDF file includes:

  • Fig. S1. Classical IL-6 signaling is required for development of colitis.
  • Fig. S2. Innate-derived IL-6 is required for TH17 pathogenicity and maintenance.
  • Fig. S3. Classical IL-6 signaling is required for maintenance of TH17 cells.
  • Fig. S4. Cotransfer of Il6ra−/− with WT TH17 cells is unable to rescue their phenotype.
  • Fig. S5. Cotransfer of Il6ra−/− with WT TH17 cells is unable to rescue their TH17 phenotype.
  • Fig. S6. IL-6Ra and gp130 expression on TH17 cells ex vivo.
  • Fig. S7. Il6ra−/− TH17 cells lose their TH17 gene expression signature in vivo.

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Other Supplementary Material for this manuscript includes the following:

  • Table S1. Full gene sets used for GSEA analysis (Excel spreadsheet).
  • Table S2. Raw data (Excel spreadsheet).

Files in this Data Supplement: