Science Immunology

The PDF file includes:

  • Supplementary Materials and Methods
  • Fig. S1. Cell quality and lineage identification of healthy and MS PBMCs and CSF.
  • Fig. S2. PHATE representation of T cells.
  • Fig. S3. Chemokine receptor flow cytometry of healthy PBMCs and CSF.
  • Fig. S4. Gating strategy for total T cell selection for surface and intracellular staining.
  • Fig. S5. Analysis of healthy TCRs.
  • Fig. S6. Analysis of MS TCRs.
  • Fig. S7. Sample sort strategy for in vitro experiments.
  • Fig. S8. Sample sort strategy for non-neuronal nuclei enrichment.
  • Fig. S9. Cell quality and lineage identification in the brain parenchyma in snRNA-seq and scRNA-seq datasets.
  • References (7887)

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Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Micosoft Excel format). Donor information.
  • Table S2 (Micosoft Excel format). Healthy T cell clusters.
  • Table S3 (Micosoft Excel format). Gene clusters and canonical pathways.
  • Table S4 (Micosoft Excel format). Healthy clonal group differentially expressed genes.
  • Table S5 (Micosoft Excel format). T cell cluster distribution statistics.
  • Table S6 (Micosoft Excel format). MS versus healthy T cell clusters differentially expressed genes.
  • Table S7 (Micosoft Excel format). MS versus healthy expanded cells differentially expressed genes.
  • Table S8 (Micosoft Excel format). T cells in brain parenchyma differentially expressed genes.
  • Table S9 (Micosoft Excel format). Cell-cell interactions using CellPhoneDB.
  • Table S10 (Micosoft Excel format). Raw data.