Science Immunology

The PDF file includes:

  • Fig. S1. Stx suppresses caspase-11–dependent inflammasome responses.
  • Fig. S2. In trans Stx expression impairs gasdermin D–dependent inflammasome responses elicited by E. coli BL21.
  • Fig. S3. Purified Stx does not induce cell death or inhibit TLR-mediated responses in macrophages.
  • Fig. S4. Multiple variants of Stx inhibit gasdermin D cleavage in response to LPS transfection.
  • Fig. S5. Catalytic activity of Stx is essential for inflammasome inhibition.
  • Fig. S6. Stx inhibits inflammasome responses elicited by LPS electroporation.
  • Fig. S7. Stx inhibits cleavage of IL-18 in colon upon infection with C. rodentium.

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Other Supplementary Material for this manuscript includes the following:

  • Table S1. Raw data file (Excel spreadsheet).