Science Immunology

The PDF file includes:

  • Materials and Methods
  • Fig. S1. Induction of autophagy upon HSV2 infection of primary fibroblasts with impaired responses in P1 and P2.
  • Fig. S2. Activation of autophagy flux by HSV2 and clinical HSV2 isolates and defective responses in patients.
  • Fig. S3. Impaired autophagy induction by HSV2 in SK-N-SH neuroblastoma cell lines deficient in ATG5 and BECN1/Beclin1.
  • Fig. S4. STING signaling and ISG responses to cGAMP, HSV1, and HSV2 in primary fibroblasts, SK-N-SH neuroblastoma cells, and THP1 cells.
  • Fig. S5. Autophagic responses, autophagy flux, and protein expression levels after reconstitution of WT gene expression in primary fibroblasts from P1 and P2.
  • Table S1. Summary of variants identified by WES of P1 and P2.
  • References (5763)

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Other Supplementary Material for this manuscript includes the following: