Science Immunology

The PDF file includes:

  • Fig. S1. Routine laboratory parameters, HScores and 4C mortality scores on admission for included hospitalized patients with COVID-19.
  • Fig. S2. Principal component analysis of all mediator values from the time of recruitment.
  • Fig. S3. Plasma mediators at the time of enrolment in patients hospitalized with COVID-19.
  • Fig. S4. Age, but not sex, is associated with differences in plasma cytokine levels within COVID-19 disease severity groups.
  • Fig. S5. Plasma mediator levels over time.
  • Fig. S6. Elevated mediator levels are apparent in the first days of symptoms in Severe COVID-19.
  • Fig. S7. Distinct inflammatory profiles between fatal influenza and COVID-19.
  • Fig. S8. GM-CSF is not elevated in fatal influenza.
  • Table S1. Patient characteristics, vital signs and routine laboratory parameters on admission for included hospitalized patients with COVID-19.
  • Table S2. Clinical characteristics of COVID-19 patient groups identified by clustering of plasma mediator values
  • Table S3. Clinical characteristics of patients with fatal influenza.
  • Table S4. Multiple linear regression of GM-CSF levels, disease status and demographic variables between patients with fatal COVID-19 and influenza.
  • The ISARIC4C investigators

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Other Supplementary Material for this manuscript includes the following:

  • Table S5. Raw data file (excel spreadsheet).