Science Immunology

The PDF file includes:

  • Supplemental Methods
  • Fig. S1. Additional characterization of pDC response to CMV-infected cells.
  • Fig. S2. Requirement of live CMV-infected cells for IFN-α response in pDC.
  • Fig. S3. LFA-1–dependent cell-to-cell contact for IFN-α production in pDC.
  • Fig. S4. TLR9-dependent recognition of CMV DNA during pDC response.
  • Fig. S5. The kinetics of pDC response to solution-born stimuli.
  • Fig. S6. The dynamics and magnitude of gene expression in activated pDCs.
  • Fig. S7. The dynamics and regulation of cell type–specific gene expression programs during pDC activation.
  • Fig. S8. Expression of cytokines and activation markers in purified pDCs and cDC2 during activation as determined by flow cytometry.
  • Fig. S9. The response of pDCs and tDCs to CMV-infected cells.
  • Fig. S10. Production of IFN-I and IFN-III by pDCs in response to Flu-infected cells.
  • Fig. S11. The effect of pDC-facilitated NK cell activation on CMV-infected cells.
  • Fig. S12. Characterization of PBMC samples from control and patients with CMV viremia.
  • Fig. S13. Additional characterization of cytokines in the plasma of patients CMV viremia.
  • Table S2. Characteristics of transplantation recipients with or without CMV viremia.
  • Legends for tables S1 and S3

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Other Supplementary Material for this manuscript includes the following:

  • Table S1. Hierarchical clustering of genes that were significantly changed during pDC activation by CMV-infected cells and by CpG (Excel file).
  • Table S3. Raw data (Excel file).