Science Immunology

The PDF file includes:

  • Fig. S1. Combination of local irradiation and αPD-1 reduces primary and metastatic tumor growth in 4T1 breast cancer model.
  • Fig. S2. T cell depletion with antibodies.
  • Fig. S3. Combinatorial treatment did not induce discernible differences between splenic CD8+ T cell populations.
  • Fig. S4. αPD-1 treatment after radiotherapy induced potent antitumor immunity.
  • Fig. S5. αPD-1 before radiotherapy enhanced the induction of double-stranded DNA breaks in CD8+ T cells in tumors but not in draining lymph nodes.
  • Fig. S6. αPD-1 before radiotherapy did not induce dysfunctional population of CD8+ T cells.
  • Table S1. Antibodies for flow cytometry used in experiments.

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Other Supplementary Material for this manuscript includes the following: