Table 1 Antibodies with severely impaired activity during persistent LCMV infection and murine SLE model. tg, transgenic; Treg cells, regulatory T cells; DCs, dendritic cells.
Specificity (clone)Species and isotypeTargetReference
Anti-hCD20
(rituximab)
Human IgG1hCD20 tg
B cells
(1, 2, 13)
Anti-hCD20 (2H7)Mouse IgG2bhCD20 tg
B cells
(1, 13)
Anti-hCD20 (8B9)Mouse IgG2a/chCD20 tg
B cells
(13)
Anti-CD20
(MB20)
Mouse IgG2a/cB cells(2)
Anti-CD20
(18B12)
Mouse IgG1B cells(13)
Anti-CD4 (GK1.5)Rat IgG2bCD4 T cells(1, 2)
Anti-CD4
(YTS191)
Rat IgG2bCD4 T cells(2)
Anti-CD25 (PC61)Rat IgG1Treg cells(1)
Anti-CD8α (2.43)Rat IgG2bCD8 T cells(1, 2)
Anti-CD8α
(53.6.72)
Rat IgG2aCD8 T cells(2)
Anti-platelets
(6A6)
Mouse IgG2a/cPlatelets(2)
Anti-LCMV-GP
(KL25)
Mouse IgG1LCMV-infected cells(2)
Anti-CD40
(FGK4.5)
Rat IgG2aDCs, B cells(1)